In this video from TEDMED 2012, Franziska Michor of Harvard University describes how very simple evolutionary processes apply to the etiology and treatment of cancer. The crux of the talk involves use of computer modeling of cancer as an evolutionary process can be used to infer drug dosing regimes that minimize the probability of resistance to the drug developing in tumor cells. As such, this is nothing new in evolutionary biology. However, she makes a more intriguing point, describing cancer as an evolutionary reversion to a single-cell paradigm within the context of a multicellular organism. At this point, such thinking may or may not have practical significance, but if nothing else, it is a nice intellectual connection between a fundamental development in evolutionary history (the rise of multicellularity) and modern disease processes.